Major cleaning the filter house

Major cleaning the filter house of the wuster column
coating systemis base on the pharmaceutical company SOP.
Therfore, before doing the major cleanyou need to read
the SOP [Standard operating procedure].Under cGMP major
clean can be done when the time limitation is expired
for example after 14 days of the last major clean.When
changing from one active ingredient to the next, if there
is some form of contamination in the run batch lot.
Or mechanical repairs in the wuster column coating system
[Glatt].To major clean the filter house ,at the OIT
lower the filters and detached it from the filter house
via the cable.Use the pressure hose to wash the debris
off the filter house wall. Turn on the hot water to
continue wash the walls of the filter house.In some
cases you might have to used a ladder to accessed the
upper part of the wall. Used recommended detergent
and recommended brushes to washed the wallof the
filter house. After scrubing and washing rinse out
the soap with theportable water.Afterward used purified
water or de-ionized water for a finalrinse. The filter
house is a difficult part of the wuster column coating system
to clean, used all safety procedure.
Some wuster column chamber are self clean also follow the SOP at all times.

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